Toxicity study

We offer a complete range of toxicology services compliant with
GLP requirements of the Chinese State Food and Drug Administration,
which is at least equivalent to OECD’s principles of good laboratory practice.

General toxicity
· Single dose toxicity study
· Repeated dose toxicity study
· Carcinogenicity study

Special toxicity
Local Irritation test, Eye toxicity test, Skin toxicity test, Antigenicity test, Photosensitivity test, Dependence test

Genetic toxicity
Ames test, Chromosome aberrant test, Micronucleus tests, DNA adducts test, TG tests, MLA test, Cell transformation test , Gene mutation test, SCG test, Cytotoxicity test

Development toxicity
· Study of fertility, early embryonic development to implantation.
· Study for effects on pre-and postnatal development, maternal function.
· Study for effects on embryo-fetal development..
· One-generation reproduction toxicity study.
· Tow-generation reproduction toxicity study.
· Prenatal development toxicity study

Safety Pharmacology
· Nervous system
· Cardiovascular system
· Respirator system
· Alimentary system

Histopathology/Pathology
· Routine examination
· Electron microscope (EM)
· Histochemistry
· Immunohistochemistry
· In situ-hybridization (ISH)